Research

Key publications

  • Rubin BK, Priftis KN, Schmidt HJ, Henke MO. Secretory hyperresponsiveness and pulmonary mucus hypersecretion. Chest 2014;146:496-507.
  • Rubin BK, Williams RW. Emerging aerosol drug delivery strategies: From bench to clinic. Adv Drug Deliv Rev 2014 doi: 10.1016/j.addr.2014.06.008
  • Strickland SL, Rubin BK, Drescher GS, Haas CF, O’Malley CA, Volsko TA, et al. AARC clinical practice guideline: effectiveness of nonpharmacologic airway clearance therapies in hospitalized patients. Respir Care 2013;58:2187-93.
  • Tanabe T, Kanoh S, Moskowitz WB, Rubin BK. Cardiac asthma: transforming growth factor-beta from the failing heart leads to squamous metaplasia in human airway cells and in the murine lung. Chest 2012;142:1274-83.
  • Tanabe T, Shimokawaji T, Kanoh S, Rubin BK. IL-33 stimulates CXCL8/IL-8 secretion in goblet cells but not normally differentiated airway cells. Clin Exp Allergy 2014;44:540-52.
  • Tokita E, Tanabe T, Asano K, Suzaki H, Rubin BK. Club cell 10-kDa protein attenuates airway mucus hypersecretion and inflammation. Eur Respir J 2014 pii: erj00809-2013
  • Nicola ML, Carvalho HB, Yoshida CT, Anjos FM, Nakao M, Santos Ude P, Cardozo KH, Carvalho VM, Pinto E, Farsky SH, Saldiva PH, Rubin BK, Nakagawa NK. Young “healthy” smokers have functional and inflammatory changes in the nasal and the lower airways. Chest. 2014;145:998-1005.
  • McNamara DG, Asher MI, Rubin BK, Stewart A, Byrnes CA. Heated humidification improves clinical outcomes, compared to a heat and moisture exchanger in children with tracheostomies. Respir Care. 2014;59:46-53
  • Dodson KM, Cohen RS, Rubin BK . Middle ear fluid characteristics in pediatric otitis media with effusion. Int J Pediatr Otorhinolaryngol. 2012;76:1806-09.
  • Kanoh S, Tanabe T, Rubin BK. IL-13-induced MUC5AC production and goblet cell differentiation is steroid resistant in human airway cells. Clin Exp Allergy 2011 Dec;41(12):1747-1756.
  • Tanabe T, Kanoh S, Tsushima K, Yamazaki Y, Kubo K, Rubin BK. Clarithromycin inhibits interleukin-13 induced goblet cell hyperplasia in human airway cells. Am J Respir Cell Mol Biol. 2011;45(5):1075-1083.
  • Kanoh S, Tanabe T, Rubin BK. Dapsone inhibits IL-8 secretion from human bronchial epithelial cells stimulated with LPS and resolves airway inflammation in the ferret. Chest 2011;140:980-990.
  • Kanoh S, Rubin BK. Macrolides as immunomodulatory medications: Mechanisms of action and clinical applications. Clinical Microbiol Rev 2010;23:590-615.
  • Voynow JA, Rubin BK. Mucus, mucins, and sputum. Chest 2009;135:505-512.